A Korean polynucleotide skin booster made from purified salmon-derived DNA, offering regenerative skin quality improvement as a more affordable alternative to REJURAN.
VITARAN (HP VITARAN) is a polynucleotide-based skin booster developed in South Korea for skin regeneration, collagen stimulation, and overall skin quality improvement. Like REJURAN, it's made from highly purified salmon-derived DNA fragments and is designed to improve hydration, elasticity, texture, and barrier function through regenerative mechanisms rather than volumization. It's CE-marked for professional aesthetic use and has gained popularity as a more affordable alternative to REJURAN in many Asian and European clinics.
VITARAN contains Polynucleotide Sodium at 20 mg/mL, purified from salmon or trout DNA through a proprietary purification and molecular optimization process. Because this DNA is highly compatible with human tissue, the PN acts as a regenerative scaffold that supports dermal repair and tissue remodeling, aiming for high purity, consistent molecular quality, and reliable handling.
Full face, neck, and décolletage - general skin rejuvenation
Under-eye area, fine wrinkles, dark circles - lower-viscosity formulation for delicate skin
Fine lines, precision areas, texture refinement, localized rejuvenation
A typical course is 4 to 6 sessions, every 2 to 3 weeks, with maintenance every 6 to 12 months. Initial hydration is usually visible within 1 to 2 weeks, early improvement at 2 to 4 weeks, and progressive collagen remodeling continues over 1 to 3 months.
Because these risks exist with any injectable or energy-based treatment, procedures should only be performed by trained, licensed medical professionals with expertise in facial anatomy.
VITARAN is CE-marked for professional use in Europe and approved for use in South Korea and several international markets. Regulatory status varies by country, so practitioners verify local approval before use.
VITARAN is an increasingly recognized PN skin booster positioned in the same regenerative category as REJURAN, using highly purified salmon and trout-derived polynucleotides to improve skin quality through collagen stimulation, tissue repair, and hydration rather than adding facial volume. Its strengths include a dedicated product range for different treatment areas, CE certification for the European market, and compatibility with combination treatments such as RF microneedling and mesotherapy devices. REJURAN currently has a longer history of clinical use and a stronger body of published evidence, making it the more established benchmark in PN-based regenerative injectables.
